In addition to taking this medicine, treatment for your high blood pressure may include weight control and a change in the foods you eat, especially foods high in sodium salt. Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet. American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. Circulation. Our Micardis telmisartan Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. One telmisartan-treated patient discontinued therapy because of increases in creatinine and blood urea nitrogen. purchase imitrex online payment australia
Check with your pharmacist about how to dispose of unused medicine. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Micardis HCT may interfere with certain lab tests, including parathyroid function tests. Be sure your doctor and lab personnel know you are taking Micardis HCT. Web MD. I am glad I am not the only one with these problems. You may take this medicine with or without food.
Dizziness, lightheadedness, or fainting may occur with this medicine, especially when you get up suddenly from a lying or sitting position. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert. If you feel dizzy, lie down so you do not faint. Then sit for a few moments before standing to prevent the dizziness from returning. Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use Micardis tablets for a condition for which it was not prescribed. Do not give Micardis tablets to other people, even if they have the same condition you have. It may harm them.
Check with your doctor right away if you become sick while taking this medicine, especially with severe or continuing nausea, vomiting, or diarrhea. These conditions may cause you to lose too much water and may lead to low blood pressure. You can also lose water by sweating, so drink plenty of water during exercise or in hot weather. Micardis may affect the way other medicines work, and other medicines may affect how Micardis works. Telmisartan is also used to lower the risk of heart attacks or stroke in patients 55 years of age and older who have diabetes or heart problems.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with not feel sick. It may take up to 4 weeks before you get the full benefit of this drug. Take this medication by mouth with or without food as directed by your doctor, usually once daily. Have your blood pressure checked regularly while taking this medication. Learn how to monitor your own blood pressure at home, and share the results with your doctor. Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. What are the ingredients in Micardis tablets? The antihypertensive effects of Micardis have been demonstrated in six principal placebo-controlled clinical trials, studying a range of 20 to 160 mg; one of these examined the antihypertensive effects of telmisartan and hydrochlorothiazide in combination. The studies involved a total of 1773 patients with mild to moderate hypertension diastolic blood pressure of 95 to 114 mmHg 1031 of whom were treated with telmisartan. Food and Drug Administration. FDA public health advisory: angiotensin-converting enzyme inhibitor ACE inhibitor drugs and pregnancy. From FDA website. Have your checked regularly while taking this medication. Learn how to monitor your own pressure at home, and share the results with your doctor. Walser M. Angiotensin-receptor blockers, type 2 diabetes, and renoprotection. N Engl J Med. BP reduction may be smaller in black patients than in patients of other races. 1 See Hypertension under Uses.
Some MEDICINES MAY INTERACT with Micardis HCT. Read this Patient Information before you start taking Micardis tablets and each time you get a refill. There may be new information. This information does not take the place of talking to your doctor about your medical condition or your treatment. Micardis must not be used in women who are more than three months pregnant. Its use during the first three months of pregnancy is not recommended. Micardis must not be used in people who have severe liver problems or bile problems. In patients with type 2 diabetes or in patients with moderate or severe kidney impairment, Micardis must also not be used in combination with aliskiren-containing medicines also used to treat essential hypertension. For the full list of restrictions, see the package leaflet. Why has Micardis been approved? Its empirical formula is C 33H 30N 4O 2, its molecular weight is 514. Initially, 40 mg once daily in adults without intravascular volume depletion. Stangier J, Su CPF, Schöndorfer G et al. Pharmacokinetics and safety of intravenous and oral telmisartan 20 mg and 120 mg in subjects with hepatic impairment compared with healthy volunteers. J Clin Pharmacol. letrozole
Boehringer Ingelheim. Micardis telmisartan tablets prescribing information. Ask your doctor before you use medicines, supplements, or salt substitutes that contain potassium. Your blood pressure will need to be checked often. Tell your doctor if your condition does not improve or if it worsens such as your remain high or increase. Micardis HCT may cause drowsiness, dizziness, or light-headedness. These effects may be worse if you take it with alcohol or certain medicines. Use Micardis HCT with caution. Micardis is used to treat essential hypertension high blood pressure in adults. apif.info doxazosin
Discontinue as soon as possible when pregnancy is detected, unless continued use is considered lifesaving. 49 50 Nearly all women can be transferred successfully to alternative therapy for the remainder of their pregnancy. If you take cholestyramine or colestipol, ask your doctor or pharmacist how to take it with Micardis HCT. Many claims are made about CoQ10. If you have diabetes, do not use telmisartan together with any medication that contains aliskiren Amturnide, Tekturna, Tekamlo, Valturna. The incidence of adverse events was not dose-related and did not correlate with gender, age, or race of patients. In placebo-controlled trials involving 1041 patients treated with various doses of Micardis 20 to 160 mg monotherapy for up to 12 weeks, the overall incidence of adverse events was similar to that in patients treated with placebo. Ask your healthcare professional how you should dispose of any medicine you do not use. Distributed into milk in rats; not known whether distributed into human milk. 1 2 Discontinue nursing or the drug. Micardis HCT should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed. Female patients of childbearing age should be told about the consequences of exposure to Micardis during pregnancy. Discuss treatment options with women planning to become pregnant. The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables. Use may lead to kidney problems. Angiotensin II is formed from angiotensin I in a reaction catalyzed by angiotensin-converting enzyme ACE, kininase II. Angiotensin II is the principal pressor agent of the renin-angiotensin system, with effects that include vasoconstriction, stimulation of synthesis and release of aldosterone, cardiac stimulation, and renal reabsorption of sodium. Telmisartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT 1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Its action is therefore independent of the pathways for angiotensin II synthesis. Who should not take Micardis? Can use the fixed combination as a substitute for the individually administered drugs. 132 Can switch to the fixed-combination preparation containing the corresponding individual doses of telmisartan and amlodipine; alternatively, can increase the dosage of one or both components for additional antihypertensive effects. Injury or death to your unborn baby. See "What is the most important information I should know about Micardis tablets? dapsone greenstone brand
Cleve Clin J Med. AstraZeneca, Wayne, PA: Personal communication on candesartan. Kidney problems, which may get worse if you already have kidney disease. You may have changes in your kidney test results, and you may need a lower dose of Micardis tablets. How should I take Micardis HCT hydrochlorothiazide and telmisartan? Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Risks of use during pregnancy. generic lopid inactive ingredients
If you have diabetes, do not use hydrochlorothiazide and telmisartan together with any medication that contains aliskiren Amturnide, Tekturna, Tekamlo, Valturna. Kaplan NM. Choice of initial therapy for hypertension. JAMA. Boehringer Ingelhein Pharmaceuticals, Inc. Twynsta telmisartan and amlodipine besylate tablets prescribing information. Ridgefield, CT; 2014 Dec. During initial clinical studies, a single case of angioedema was reported among a total of 3781 patients treated. Hg may still be considered. In rare cases, telmisartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine. Use of telmisartan in fixed combination with hydrochlorothiazide is not recommended in patients with severe hepatic impairment. The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. Anon. Drugs for hypertension. Med Lett Drugs Ther. Avoid drinking alcohol. It can lower your blood pressure and may increase some of the side effects of telmisartan. Hg is 26, 22, or 55% with telmisartan 80 mg daily alone, amlodipine 10 mg daily alone, or telmisartan combined with amlodipine same dosages respectively. Wright JT, Fine LJ, Lackland DT et al. Evidence supporting a systolic blood pressure goal of less than 150 mm Hg in patients aged 60 years or older: the minority view. Ann Intern Med. Tablets should not be removed from blisters until immediately before administration. Lithium: Reversible increases in serum lithium concentrations and toxicity have been reported during concomitant administration of lithium with angiotensin II receptor antagonists including Micardis. Therefore, monitor serum lithium levels during concomitant use. Symptoms may include fainting; fast, slow, or irregular heartbeat; severe or unusual dizziness; symptoms of blood electrolyte problems eg, confusion; irregular heartbeat; mental or mood changes; muscle pain, weakness, or cramping; seizures; sluggishness; symptoms of dehydration eg, drowsiness; dry eyes; fast heartbeat; nausea; restlessness; unusual thirst, tiredness, or weakness; vomiting. Micardis or ramipril alone.
Deterioration of renal function may occur. 1 2 See Renal Effects under Cautions. When used in fixed combination with amlodipine or hydrochlorothiazide, consider the cautions, precautions, and contraindications associated with the concomitant agent. As a consequence of inhibiting the renin-angiotensin-aldosterone system, anticipate changes in renal function in susceptible individuals. Report prolonged or to your doctor. Be sure to drink enough fluids to prevent unless your doctor directs you otherwise. The way dietary supplements are manufactured may not be standardized. Because of this, how well they work or any side effects they cause may differ among brands or even within different lots of the same brand. The form of supplement that you buy in health food or grocery stores may not be the same as the form used in research. Use Micardis HCT as directed by your doctor. Check the label on the medicine for exact dosing instructions. Lifestyle changes that may help this medication work better include stress reduction programs, exercise, and dietary changes. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Read the Patient Information Leaflet if available from your pharmacist before you start taking telmisartan and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Dosage adjustments may be necessary. 2 See Hepatic Impairment under Dosage and Administration. No dosage adjustment is necessary in patients with decreased renal function. The information contained in the Truven Health Micromedex products as delivered by Drugs. Use Micardis HCT with caution in the ELDERLY; they may be more sensitive to its effects. Antihypertensive effect evident within 2 weeks, with maximum BP reduction after 4 weeks. PREGNANCY and BREAST-FEEDING: Micardis HCT may cause birth defects or fetal death if you take it while you are pregnant. If you think you may be pregnant, contact your doctor right away. Micardis HCT is found in breast milk. Do not breast-feed while taking Micardis HCT. But the National Cancer Institute NCI rates the strength of the evidence for CoQ10 and cancer as weak. repaglinide
Other Drugs: Co-administration of telmisartan did not result in a clinically significant interaction with acetaminophen, amlodipine, glyburide, simvastatin, hydrochlorothiazide, warfarin, or ibuprofen. Telmisartan is not metabolized by the cytochrome P450 system and had no effects in vitro on cytochrome P450 enzymes, except for some inhibition of CYP2C19. Telmisartan is not expected to interact with drugs that inhibit cytochrome P450 enzymes; it is also not expected to interact with drugs metabolized by cytochrome P450 enzymes, except for possible inhibition of the metabolism of drugs metabolized by CYP2C19. This list is not complete. Other drugs may interact with telmisartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. Micardis is available as tablets for oral administration, containing 20 mg, 40 mg or 80 mg of telmisartan. The tablets contain the following inactive ingredients: sodium hydroxide, meglumine, povidone, sorbitol, and magnesium stearate. Micardis tablets are hygroscopic and require protection from moisture. Do not crush, chew, or break a telmisartan tablet. Swallow it whole. Nissen SE. Angiotensin-receptor blockers and cancer: urgent regulatory review needed. Lancet Oncol. Not metabolized by CYP isoenzymes; has no effect on CYP isoenzymes except for some inhibition of CYP2C19 in vitro. American Heart Association Task Force on Practice Guidelines. Circulation. McMurray JJ, Packer M, Desai AS et al. Angiotensin-neprilysin inhibition versus enalapril in heart failure. N Engl J Med. buy sotalol in bangkok
ACE inhibitor or angiotensin II receptor antagonist therapy. Food and Drug Administration. FDA drug safety communication: No increase in risk of cancer with certain blood pressure drugs-angiotensin receptor blockers ARBs. Rockville, MD; 2011 Jun 2. Available from FDA website. Possible fetal and neonatal morbidity and mortality when used during pregnancy. 1 2 50 See Boxed Warning. When used for initial therapy of hypertension in patients likely to require combination therapy with multiple antihypertensive agents, usual initial dosage is telmisartan 40 mg and amlodipine 5 mg once daily; initial dosage of telmisartan 80 mg and amlodipine 5 mg once daily may be used in patients requiring larger BP reductions. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. For the treatment of high blood pressure, it may take up to 4 weeks before you get the full benefit of this drug. If you have high blood pressure, do not use nonprescription products that contain stimulants. These products may include diet pills or cold medicines. Contact your doctor if you have any questions or concerns. iressa cost
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It is not known if Micardis passes into your breast milk. You and your doctor should decide if you will take Micardis tablets or breast-feed. You should not do both. Talk with your doctor about the best way to feed your baby if you take Micardis tablets. Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure. The fifth report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure JNC V. Arch Intern Med. Adams W, Bratt DE. Young coconut water for home rehydration in children with mild gastroenteritis.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Does not share the ACE inhibitor common adverse effect of dry cough. Distributed into milk in rats; not known whether distributed into human milk. No substantial differences in safety or efficacy relative to younger adults, but increased sensitivity cannot be ruled out.
Older adults may be more sensitive to the side effects of this drug, especially dizziness and change in the amount of urine problems. In the prevention of cardiovascular problems, Micardis had a similar effect to ramipril, with around 17% of patients dying, being admitted to hospital because of cardiovascular problems, or having a heart attack or stroke. The combination of the two medicines was no more effective than either medicine taken alone and was linked to an increased risk of side effects. What is the risk associated with Micardis? Martineau P, Goulet J. New competition in the realm of renin-angiotensin axis inhibition; the angiotensin II receptor antagonists in congestive heart failure. Ann Pharmacother.
Ask your health care provider any questions you may have about how to use Micardis HCT. Rare cases of rhabdomyolysis have been reported in patients receiving angiotensin II receptor blockers, including Micardis. Weber MA, Schiffrin EL, White WB et al. Clinical practice guidelines for the management of hypertension in the community: a statement by the American Society of Hypertension and the International Society of Hypertension. J Clin Hypertens Greenwich. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.